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Ameloss 5mg Tablet 10pcs
Ameloss (Donepezil Hydrochloride) is indicated for the symptomatic treatment of mild to moderate dementia of the Alzheimer’s type.
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✅ Description:
Alzheimer's disease is a progressive brain disorder that leads to dementia, which significantly affects a person's memory, thinking, and social abilities. Over time, it destroys important mental functions in the brain, making daily activities increasingly difficult.
- Often the first and most noticeable symptom. People may forget recent events, conversations, or names, even of close family members.
- Difficulty with time, place, or recognizing familiar faces and places.
- Mood swings, irritability, depression, and personality shifts are common, along with difficulty managing emotions.
- Gradual impairment in thinking and decision-making abilities, affecting tasks like problem-solving, judgment, and planning.
As the disease progresses, these symptoms worsen, making it hard for the person to function independently. There is currently no cure for Alzheimer's, but treatments like Donepezil (Ameloss) can help manage symptoms and improve quality of life by temporarily improving cognitive function.
Safety Advices
Alcohol
UNSAFE
Avoid consumption of alcohol while taking Ameloss 5 because it may alter the effect of this medicine.
Pregnancy
CONSULT YOUR DOCTOR
Ameloss 5 is generally not recommended for use during pregnancy unless it is considered necessary. Consult your doctor before taking Ameloss 5.
Breastfeeding
CONSULT YOUR DOCTOR
Ameloss 5 is not recommended for use in breastfeeding women. Consult your doctor before taking Ameloss 5.
Driving
UNSAFE
Ameloss 5 may cause tiredness, dizziness, and muscle cramps which could affect your ability to drive or operate machines. If you experience these side effects, do not drive or operate machines. Consult your doctor before taking Ameloss 5.
Kidney
CONSULT YOUR DOCTOR
Ameloss 5 should be used with caution in patients with mild kidney disease. Consult your doctor before taking Ameloss 5.
Liver
CONSULT YOUR DOCTOR
Ameloss 5 is not recommended for use in patients with severe liver disease. It should be used with caution in patients with liver problems or hepatitis. Consult your doctor before taking Ameloss 5.
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✔️ Uses of Ameloss 5
- Used to manage mild to moderately severe Alzheimer’s dementia
✔️ How does Ameloss 5 work?
It works by increasing the level of acetylcholine and helps in controlling the symptoms of the disease.
✔️ Side Effects of Ameloss 5
Nausea, Diarrhea, Insomnia (difficulty in sleeping), Weight loss, Accidental injury
✔️ Quick Suggestions:
- Ameloss 5 does not cure Alzheimer's disease but may help improve brain function and the ability to do daily activities.
- Take it with or without food, preferably at night before going to bed.
- It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Donepezil.
- Monitor your body weight regularly as both Donepezil and Alzheimer's disease can cause weight loss.
- Do not drive or do anything that requires mental focus until you know how Donepezil affects you.
- Be cautious while taking this medicine if you suffer from peptic ulcer as it may cause vomiting, stomach bleeding, stomach pain, or discomfort.
- Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease.
- Inform your doctor if you experience seizures or convulsions while taking this medicine.
✔️ Indication of Ameloss 5
Donepezil is used in the treatment of dementia associated with Alzheimer's disease. It is not recommended in patients with gastrointestinal bleeding and lung diseases.
✔️ Pharmacology
Donepezil Hydrochloride is a centrally-acting anticholinesterase agent. It binds reversibly to acetylcholinesterase, inhibiting the hydrolysis of acetylcholine, leading to an increase in acetylcholine concentration at cholinergic synapses in the brain, which may improve cognitive function in Alzheimer's disease.
✔️ Dosage & Administration of Ameloss 5
- Initial Dose: 5 mg once daily at bedtime for at least one month to assess clinical response and to achieve steady-state concentrations.
- Dose Adjustment: After one month, the dose may be increased to 10 mg once daily.
- Renal & Hepatic Impairment: No dose adjustment is required for mild to moderate impairment.
- Pediatric Use: Not recommended, as there are no adequate safety and efficacy trials in children.
Take Donepezil at the same time every day. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not take this medicine if you have any gastrointestinal disease and lung diseases.
✔️ Interaction
- Avoid Anticholinergic drugs (e.g., atropine, benztropine) as they may counteract the effects of Donepezil.
- May reduce Donepezil’s effect: Carbamazepine, dexamethasone, phenobarbital, phenytoin.
- May increase Donepezil’s effect: Ketoconazole, quinidine, cimetidine.
✔️ Contraindications
Hypersensitivity to Donepezil Hydrochloride or piperidine derivatives.
✔️ Pregnancy & Lactation
- Pregnancy: Use only if the potential benefit outweighs the potential risk to the fetus, as there are no adequate studies in pregnant women.
- Lactation: It is unknown if Donepezil is excreted in human breast milk; not recommended for nursing mothers.
✔️ Precautions & Warnings
- Use with caution in patients with:
- Sick sinus syndrome or other heart conduction issues.
- Risk of peptic ulcers.
- Asthma or obstructive airway disease.
- Undergoing anesthesia.
✔️ Storage:
- Store below 30°C, protected from light and moisture.
- Keep out of reach of children.
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